International Journal of Women's Health and Reproduction Sciences

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Jan 2018, Vol 6, Issue 1

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Original Article
Can Follicular Fluid Anti-Mullerian Hormone Level Be a Determinant of Pregnancy in Women Under 35 Years of Age?
Turabi Yilmaz¹, Safak Tavukcuoglu¹, Seval Tasdemir¹, Semra Esenkaya¹, Tülay İrez²
¹Ferti-Jin In Vitro Fertilization Center, Istanbul, Turkey ²Department of Histology and Embryology, Medical Faculty, Biruni University, Istanbul, Turkey
IJWHR 2018; 6: 006-010 DOI: 10.15296/ijwhr.2018.03 Viewed : 3958 times Downloaded : 3682 times. Keywords : Anti-Mullerian hormone, Clinical pregnancy, Embryo, Follicular Fluid, In vitro fertilization, Oocyte
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Abstract

Objectives: The failure of oocyte morphological assessment to predict in vitro fertilization (IVF) outcome has led the researchers to examine biochemical criteria of follicular fluid (FF). Anti-Mullerian hormone (AMH), an important marker of ovarian reserve, is secreted by the granulosa cells. The aim of this study is to investigate the relationship between the FF (AMH) levels and oocyte, embryo quality, fertilization, and clinical pregnancy. Materials and Methods: The FF (AMH) levels of 61 patients (mean age: 33.72 ± 4.82 years; range: 21 to 42 years) were analyzed. The FF (AMH) levels were measured by the quantitative auto-analyzer with an electro-chemiluminescence assay. Results: The FF (AMH) levels in patients under 35 years of age were higher in pregnant women than non-pregnant ones (P<0.01). Conclusion: Our study results showed that the FF (AMH) levels were correlated with the quality of oocyte and embryo and were the predictors of clinical pregnancy in patients younger than 35 years of age.