International Journal of Women's Health and Reproduction Sciences

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Oct 2019, Vol 7, Issue 4

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Original Article
Comparative Investigation of the Sensitivity of Candida Fungi Isolated From Vulvovaginal Candidiasis to Nystatin and Teucrium polium Smoke Product
Marzieh Akbarzdeh¹, Batool Bonyadpour², Kayvan Pakshir³⁴, Abdol Ali Mohagheghzadeh⁴
¹Maternal-fetal Medicine Research Center, Department of Midwifery, School of Nursing and Midwifery, Shiraz University of Medical Sciences. Shiraz, Iran ²Department of Midwifery, Islamic Azad University, Shahr-e-Babak Branch, Iran ³Department of Parasitology and Mycology, Central Basic Research in Infectious Diseases, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran ⁴Department of Traditional Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran
IJWHR 2019; 7: 508-514 DOI: 10.15296/ijwhr.2019.84 Viewed : 3826 times Downloaded : 2104 times. Keywords : Vulvovaginal candidiasis, Albicans, Nystatin, Teucrium Polium, Smoke, Persian medicine
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Abstract

Objectives: The present study aimed to compare the antifungal activities of Teucrium Polium smoke product and nystatin in the treatment of Candida vaginitis in vitro. Materials and Methods: In this quasi-experimental study, 105 subjects were diagnosed with Candida vaginitis. The data were collected through a collection form and the species were isolated by the germ tube, as well as CHROMagar chromogenic and chlamydospore formation tests. Results: Based on the results of the germ tube, chlamydospore formation, and CHROMagar tests, 70.5%, 23.8%, and 66.6% of the species were Candida albicans, respectively. In addition, 99% of the samples were sensitive to nystatin. A significant relationship was also observed between the antifungal drug and the type of organism (P<0.02). Finally, all the 15 standard clinical samples were sensitive to T. polium smoke. Conclusions: In general, the results confirmed the antifungal effects of T. polium and nystatin on the species isolated from 10 clinical samples obtained from Candida vaginitis as well as on five standard strains.