International Journal of Women's Health and Reproduction Sciences

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Jan 2023, Vol 11, Issue 1

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Case Report
Is There any Effect of COVID-19 on Follicular Environment in Women Underwent ART?
Nafiye Yılmaz¹, Zehra Kurdoglu², Caner Özer³, Sibel Aydogan⁴, Özlem Moraloglu Tekin¹
¹Department of ART, Gulhane Medical Faculty, University of Health Sciences Turkey, Ankara City Hospital, Ankara, Turkey ²Department of Obstetrics and Gynecology subdivision of ART, Faculty of Medicine, Ankara Yildirim Beyazıt University, Ankara City Hospital, Ankara, Turkey ³Department of Histology and Embryology, Ankara City Hospital, Ankara, Turkey⁴Department of Microbiology, Ankara City Hospital, Ankara, Turkey
IJWHR 2023; 11: 042-043 DOI: 10.15296/ijwhr.2023.08 Viewed : 2444 times Downloaded : 1649 times. Keywords : SARS-COV-2, In vitro fertilization, Oocyte retrieval, Follicular fluid, Embryo culture medium
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Abstract

There is insufficient data on the impact of severe acute respiratory coronavirus-2 (SARS-CoV-2) on the reproductive tissues, its possible risk of cross-contamination, transmission and adverse effect on in vitro fertilization (IVF) outcome. Until today, there is no report associated with viral RNA in both follicular fluid and embryo culture medium from SARS-COV-2 positive women. In this case report, a 24-year-old woman with SARS-CoV-2 was presented. We investigated the SARS-COV-2 positivity in the follicular fluid and embryo culture medium of mildly symptomatic woman on oocyte pick up (OPU) day. We could not detect viral RNA in neither the follicular fluid nor the embryo culture medium. In addition, although the response of ovarian stimulation was normal, the number and maturity of the retrieved oocytes were low.